| Reaction Details |
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 | Report a problem with these data |
| Target | Monoglyceride lipase |
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| Ligand | BDBM50295686 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_577779 (CHEMBL1053086) |
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| IC50 | 3300±n/a nM |
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| Citation |  Minkkilä, A; Myllymäki, MJ; Saario, SM; Castillo-Melendez, JA; Koskinen, AM; Fowler, CJ; Leppänen, J; Nevalainen, T The synthesis and biological evaluation of para-substituted phenolic N-alkyl carbamates as endocannabinoid hydrolyzing enzyme inhibitors. Eur J Med Chem44:2994-3008 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Monoglyceride lipase |
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| Name: | Monoglyceride lipase |
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| Synonyms: | MAGL | MGLL_RAT | Mgl2 | Mgll | Monoacylglycerol lipase | Monoglyceride lipase | Monoglyceride lipase (MGL) |
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| Type: | Enzyme |
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| Mol. Mass.: | 33505.38 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q8R431 |
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| Residue: | 303 |
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| Sequence: | MPEASSPRRTPQNVPYQDLPHLVNADGQYLFCRYWKPSGTPKALIFVSHGAGEHCGRYDE
LAQMLKRLDMLVFAHDHVGHGQSEGERMVVSDFQVFVRDLLQHVNTVQKDYPEVPVFLLG
HSMGGAISILAAAERPTHFSGMILISPLILANPESASTLKVLAAKLLNFVLPNISLGRID
SSVLSRNKSEVDLYNSDPLICHAGVKVCFGIQLLNAVSRVERAMPRLTLPFLLLQGSADR
LCDSKGAYLLMESSPSQDKTLKMYEGAYHVLHKELPEVTNSVLHEINTWVSHRIAVAGAR
CLP
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| BDBM50295686 |
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| n/a |
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| Name | BDBM50295686 |
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| Synonyms: | 4-(Dodecylcarbamoyloxy)benzoic acid methyl ester | CHEMBL552117 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H33NO4 |
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| Mol. Mass. | 363.491 |
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| SMILES | CCCCCCCCCCCCNC(=O)Oc1ccc(cc1)C(=O)OC |
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| Structure | 
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