| Reaction Details |
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 | Report a problem with these data |
| Target | Macrophage migration inhibitory factor |
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| Ligand | BDBM50298005 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_585090 (CHEMBL1054356) |
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| IC50 | >100000±n/a nM |
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| Citation |  Balachandran, S; Rodge, A; Gadekar, PK; Yadav, VN; Kamath, D; Chetrapal-Kunwar, A; Bhatt, P; Srinivasan, S; Sharma, S; Vishwakarma, RA; Dagia, NM Novel derivatives of ISO-1 as potent inhibitors of MIF biological function. Bioorg Med Chem Lett19:4773-6 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Macrophage migration inhibitory factor |
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| Name: | Macrophage migration inhibitory factor |
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| Synonyms: | GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase |
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| Type: | Enzyme |
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| Mol. Mass.: | 12478.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14174 |
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| Residue: | 115 |
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| Sequence: | MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
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| BDBM50298005 |
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| n/a |
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| Name | BDBM50298005 |
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| Synonyms: | 2-fluoro-4-(5-(5-methyl-1,2,4-oxadiazol-3-yl)-4,5-dihydroisoxazol-3-yl)phenol | CHEMBL565030 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H10FN3O3 |
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| Mol. Mass. | 263.2245 |
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| SMILES | Cc1nc(no1)C1CC(=NO1)c1ccc(O)c(F)c1 |c:9| |
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| Structure | 
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