| Reaction Details |
|---|
 | Report a problem with these data |
| Target | C5a anaphylatoxin chemotactic receptor 1 |
|---|
| Ligand | BDBM50305737 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_604754 (CHEMBL1072548) |
|---|
| IC50 | >60000±n/a nM |
|---|
| Citation |  Chen, JJ; Cole, DC; Ciszewski, G; Crouse, K; Ellingboe, JW; Nowak, P; Tawa, GJ; Berstein, G; Li, W Identification of a new class of small molecule C5a receptor antagonists. Bioorg Med Chem Lett20:662-4 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| C5a anaphylatoxin chemotactic receptor 1 |
|---|
| Name: | C5a anaphylatoxin chemotactic receptor 1 |
|---|
| Synonyms: | C5AR1_RAT | C5a anaphylatoxin chemotactic receptor | C5ar1 | C5r1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 39427.21 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_604754 |
|---|
| Residue: | 352 |
|---|
| Sequence: | MDPISNDSSEITYDYSDGTPNPDMPADGVYIPKMEPGDIAALIIYLAVFLVGVTGNALVV
WVTAFEAKRTVNAIWFLNLAVADLLSCLALPILFTSIVKHNHWPFGDQACIVLPSLILLN
MYSSILLLATISADRFLLVFKPIWCQKFRRPGLAWMACGVTWVLALLLTIPSFVFRRIHK
DPYSDSILCNIDYSKGPFFIEKAIAILRLMVGFVLPLLTLNICYTFLLIRTWSRKATRST
KTLKVVMAVVTCFFVFWLPYQVTGVILAWLPRSSSTFQSVERLNSLCVSLAYINCCVNPI
IYVMAGQGFHGRLRRSLPSIIRNVLSEDSLGRDSKSFTRSTMDTSTQKSQAV
|
|
|
|---|
| BDBM50305737 |
|---|
| n/a |
|---|
| Name | BDBM50305737 |
|---|
| Synonyms: | CHEMBL604277 | N,N'-(1,2-phenylene)bis(N-allyl-4-methylbenzenesulfonamide) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H28N2O4S2 |
|---|
| Mol. Mass. | 496.642 |
|---|
| SMILES | Cc1ccc(cc1)S(=O)(=O)N(CC=C)c1ccccc1N(CC=C)S(=O)(=O)c1ccc(C)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
