| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50313165 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_616815 (CHEMBL1099399) |
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| Ki | 83000±n/a nM |
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| Citation |  Kurasaki, H; Okamoto, I; Morita, N; Tamura, O Synthesis and evaluation of opioid receptor-binding affinity of elaeocarpenine and its analogs. Bioorg Med Chem Lett20:1601-3 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | KOR-1 | Kappa Opioid Receptor | OPIATE Kappa | OPRK_RAT | Opioid receptor | Oprk1 | Ror-d |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42692.90 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P34975 |
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| Residue: | 380 |
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| Sequence: | MESPIQIFRGEPGPTCAPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAVLSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRV
RNTVQDPASMRDVGGMNKPV
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| BDBM50313165 |
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| n/a |
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| Name | BDBM50313165 |
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| Synonyms: | (S)-(1,2,3,5,6,8a-hexahydroindolizin-8-yl)(2-hydroxyphenyl)methanone | CHEMBL1080153 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H17NO2 |
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| Mol. Mass. | 243.301 |
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| SMILES | Oc1ccccc1C(=O)C1=CCCN2CCC[C@@H]12 |r,t:10| |
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| Structure | 
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