| Reaction Details |
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 | Report a problem with these data |
| Target | Aminodeoxychorismate lyase |
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| Ligand | BDBM50317150 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_630879 (CHEMBL1113008) |
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| Ki | 5700000±n/a nM |
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| Citation |  Ziebart, KT; Dixon, SM; Avila, B; El-Badri, MH; Guggenheim, KG; Kurth, MJ; Toney, MD Targeting multiple chorismate-utilizing enzymes with a single inhibitor: validation of a three-stage design. J Med Chem53:3718-29 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aminodeoxychorismate lyase |
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| Name: | Aminodeoxychorismate lyase |
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| Synonyms: | PABC_ECOLI | pabC |
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| Type: | PROTEIN |
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| Mol. Mass.: | 29714.75 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | ChEMBL_630879 |
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| Residue: | 269 |
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| Sequence: | MFLINGHKQESLAVSDRATQFGDGCFTTARVIDGKVSLLSAHIQRLQDACQRLMISCDFW
PQLEQEMKTLAAEQQNGVLKVVISRGSGGRGYSTLNSGPATRILSVTAYPAHYDRLRNEG
ITLALSPVRLGRNPHLAGIKHLNRLEQVLIRSHLEQTNADEALVLDSEGWVTECCAANLF
WRKGNVVYTPRLDQAGVNGIMRQFCIRLLAQSSYQLVEVQASLEESLQADEMVICNALMP
VMPVCACGDVSFSSATLYEYLAPLCERPN
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| BDBM50317150 |
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| n/a |
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| Name | BDBM50317150 |
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| Synonyms: | CHEMBL1088356 | N-((S)-6-Amino-1-((S)-1-amino-3-(3-chlorophenyl)-1-oxopropan-2-ylamino)-1-oxohexan-2-yl)-3-hydroxy-4-methyl-2-nitrobenzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C23H28ClN5O6 |
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| Mol. Mass. | 505.951 |
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| SMILES | Cc1ccc(C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2cccc(Cl)c2)C(N)=O)c(c1O)[N+]([O-])=O |r| |
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| Structure | 
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