| Reaction Details |
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 | Report a problem with these data |
| Target | Urotensin-2 receptor |
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| Ligand | BDBM50320475 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_636753 (CHEMBL1167042) |
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| IC50 | 67±n/a nM |
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| Citation |  Maryanoff, BE; Kinney, WA Urotensin-II receptor modulators as potential drugs. J Med Chem53:2695-708 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Urotensin-2 receptor |
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| Name: | Urotensin-2 receptor |
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| Synonyms: | G-protein coupled receptor 14 | GPR14 | UR-II-R | UR2R_HUMAN | UTS2R | Urotensin II receptor | Urotensin-II |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42159.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Urotensin-II UTS2R HUMAN::Q9UKP6 |
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| Residue: | 389 |
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| Sequence: | MALTPESPSSFPGLAATGSSVPEPPGGPNATLNSSWASPTEPSSLEDLVATGTIGTLLSA
MGVVGVVGNAYTLVVTCRSLRAVASMYVYVVNLALADLLYLLSIPFIVATYVTKEWHFGD
VGCRVLFGLDFLTMHASIFTLTVMSSERYAAVLRPLDTVQRPKGYRKLLALGTWLLALLL
TLPVMLAMRLVRRGPKSLCLPAWGPRAHRAYLTLLFATSIAGPGLLIGLLYARLARAYRR
SQRASFKRARRPGARALRLVLGIVLLFWACFLPFWLWQLLAQYHQAPLAPRTARIVNYLT
TCLTYGNSCANPFLYTLLTRNYRDHLRGRVRGPGSGGGRGPVPSLQPRARFQRCSGRSLS
SCSPQPTDSLVLAPAAPARPAPEGPRAPA
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| BDBM50320475 |
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| n/a |
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| Name | BDBM50320475 |
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| Synonyms: | 1-(2-(1-(2,5-difluorophenethyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)-3-(2-methylquinolin-4-yl)urea | CHEMBL1163360 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H34F2N4O3 |
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| Mol. Mass. | 560.6342 |
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| SMILES | COc1cc2CCN(CCNC(=O)Nc3cc(C)nc4ccccc34)C(CCc3cc(F)ccc3F)c2cc1OC |
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| Structure | 
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