| Reaction Details |
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 | Report a problem with these data |
| Target | B-cell receptor CD22 |
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| Ligand | BDBM50320699 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_638728 (CHEMBL1169089) |
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| Kd | 2000000±n/a nM |
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| Citation |  Hanashima, S; Sato, K; Naito, Y; Takematsu, H; Kozutsumi, Y; Ito, Y; Yamaguchi, Y Synthesis and binding analysis of unique AG2 pentasaccharide to human Siglec-2 using NMR techniques. Bioorg Med Chem18:3720-5 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| B-cell receptor CD22 |
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| Name: | B-cell receptor CD22 |
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| Synonyms: | CD22 | CD22_HUMAN | SIGLEC2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 95348.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_727026 |
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| Residue: | 847 |
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| Sequence: | MHLLGPWLLLLVLEYLAFSDSSKWVFEHPETLYAWEGACVWIPCTYRALDGDLESFILFH
NPEYNKNTSKFDGTRLYESTKDGKVPSEQKRVQFLGDKNKNCTLSIHPVHLNDSGQLGLR
MESKTEKWMERIHLNVSERPFPPHIQLPPEIQESQEVTLTCLLNFSCYGYPIQLQWLLEG
VPMRQAAVTSTSLTIKSVFTRSELKFSPQWSHHGKIVTCQLQDADGKFLSNDTVQLNVKH
TPKLEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTTVSWLKDGTSLKKQNTFTLNLREVT
KDQSGKYCCQVSNDVGPGRSEEVFLQVQYAPEPSTVQILHSPAVEGSQVEFLCMSLANPL
PTNYTWYHNGKEMQGRTEEKVHIPKILPWHAGTYSCVAENILGTGQRGPGAELDVQYPPK
KVTTVIQNPMPIREGDTVTLSCNYNSSNPSVTRYEWKPHGAWEEPSLGVLKIQNVGWDNT
TIACAACNSWCSWASPVALNVQYAPRDVRVRKIKPLSEIHSGNSVSLQCDFSSSHPKEVQ
FFWEKNGRLLGKESQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSM
SPGDQVMEGKSATLTCESDANPPVSHYTWFDWNNQSLPYHSQKLRLEPVKVQHSGAYWCQ
GTNSVGKGRSPLSTLTVYYSPETIGRRVAVGLGSCLAILILAICGLKLQRRWKRTQSQQG
LQENSSGQSFFVRNKKVRRAPLSEGPHSLGCYNPMMEDGISYTTLRFPEMNIPRTGDAES
SEMQRPPPDCDDTVTYSALHKRQVGDYENVIPDFPEDEGIHYSELIQFGVGERPQAQENV
DYVILKH
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| BDBM50320699 |
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| n/a |
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| Name | BDBM50320699 |
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| Synonyms: | (2R,4S,5R,6S)-5-acetamido-2-((2S,3R,4S,5S,6R)-2-((2R,3R,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-(2-(trimethylsilyl)ethoxy)tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yloxy)-4-((3S,4R,5S)-4-((2S,3R,4R,5S)-5-((R)-1,2-dihydroxyethyl)-3,4-dihydroxytetrahydrofuran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylic acid | CHEMBL1163267 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H71NO29Si |
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| Mol. Mass. | 1058.0665 |
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| SMILES | CC(=O)N[C@@H]1[C@H](C[C@@](O[C@H]2[C@@H](O)[C@@H](CO)O[C@@H](O[C@@H]3[C@@H](CO)O[C@@H](OCC[Si](C)(C)C)[C@H](O)[C@H]3O)[C@@H]2O)(O[C@@H]1[C@H](O)[C@H](O)CO)C(O)=O)O[C@H]1O[C@H](CO)[C@H](O)[C@H](O[C@@H]2O[C@@H]([C@H](O)CO)[C@H](O)[C@H]2O)[C@H]1O |r| |
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| Structure | 
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