| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM50328472 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_665589 (CHEMBL1261473) |
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| Ki | 523±n/a nM |
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| Citation |  Vázquez-Villa, H; González-Vera, JA; Benhamú, B; Viso, A; Fernández de la Pradilla, R; Junquera, E; Aicart, E; López-Rodríguez, ML; Ortega-Gutiérrez, S Development of molecular probes for the human 5-HT(6) receptor. J Med Chem53:7095-106 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 46968.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50406 |
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| Residue: | 440 |
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| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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| BDBM50328472 |
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| n/a |
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| Name | BDBM50328472 |
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| Synonyms: | 4-{5-[4-(Dimethylamino)phenyl]-1,3-oxazol-2-yl}-N-(4-methoxy-3-piperazin-1-ylphenyl)benzenesulfonamide | CHEMBL1258714 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H31N5O4S |
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| Mol. Mass. | 533.642 |
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| SMILES | COc1ccc(NS(=O)(=O)c2ccc(cc2)-c2ncc(o2)-c2ccc(cc2)N(C)C)cc1N1CCNCC1 |
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| Structure | 
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