| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Fructose-bisphosphate aldolase |
|---|
| Ligand | BDBM50330435 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_684841 (CHEMBL1286071) |
|---|
| Ki | 800±n/a nM |
|---|
| Citation |  Daher, R; Coinçon, M; Fonvielle, M; Gest, PM; Guerin, ME; Jackson, M; Sygusch, J; Therisod, M Rational design, synthesis, and evaluation of new selective inhibitors of microbial class II (zinc dependent) fructose bis-phosphate aldolases. J Med Chem53:7836-42 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Fructose-bisphosphate aldolase |
|---|
| Name: | Fructose-bisphosphate aldolase |
|---|
| Synonyms: | 37 kDa major allergen | ALF_CANAL | FBA1 | FBP aldolase | FBPA | Fructose-1,6-bisphosphate aldolase | IgE-binding allergen |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 39211.38 |
|---|
| Organism: | Candida albicans |
|---|
| Description: | ChEMBL_684841 |
|---|
| Residue: | 359 |
|---|
| Sequence: | MAPPAVLSKSGVIYGKDVKDLFDYAQEKGFAIPAINVTSSSTVVAALEAARDNKAPIILQ
TSQGGAAYFAGKGVDNKDQAASIAGSIAAAHYIRAIAPTYGIPVVLHTDHCAKKLLPWFD
GMLKADEEFFAKTGTPLFSSHMLDLSEETDDENIATCAKYFERMAKMGQWLEMEIGITGG
EEDGVNNEHVEKDALYTSPETVFAVYESLHKISPNFSIAAAFGNVHGVYKPGNVQLRPEI
LGDHQVYAKKQIGTDAKHPLYLVFHGGSGSTQEEFNTAIKNGVVKVNLDTDCQYAYLTGI
RDYVTNKIEYLKAPVGNPEGADKPNKKYFDPRVWVREGEKTMSKRIAEALDIFHTKGQL
|
|
|
|---|
| BDBM50330435 |
|---|
| n/a |
|---|
| Name | BDBM50330435 |
|---|
| Synonyms: | 4-(N-hydroxy-2-(phosphonooxy)acetamido)butyl dodecanoate | CHEMBL1278173 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H36NO8P |
|---|
| Mol. Mass. | 425.4541 |
|---|
| SMILES | CCCCCCCCCCCC(=O)OCCCCN(O)C(=O)COP(O)(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
