| Reaction Details |
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 | Report a problem with these data |
| Target | Fructose-bisphosphate aldolase |
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| Ligand | BDBM50330438 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_684842 (CHEMBL1286072) |
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| Ki | 13±n/a nM |
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| Citation |  Daher, R; Coinçon, M; Fonvielle, M; Gest, PM; Guerin, ME; Jackson, M; Sygusch, J; Therisod, M Rational design, synthesis, and evaluation of new selective inhibitors of microbial class II (zinc dependent) fructose bis-phosphate aldolases. J Med Chem53:7836-42 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Fructose-bisphosphate aldolase |
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| Name: | Fructose-bisphosphate aldolase |
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| Synonyms: | ALF_MYCTU | FBP aldolase | FBPA | Fructose-1,6-bisphosphate aldolase | Fructose-1,6-bisphosphate aldolase (FBA) | Fructose-bisphosphate aldolase | Probable fructose-bisphosphate aldolase Fba | fba |
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| Type: | Protein |
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| Mol. Mass.: | 36539.01 |
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| Organism: | Mycobacterium tuberculosis (strain H37Rv) |
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| Description: | P9WQA3 |
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| Residue: | 344 |
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| Sequence: | MPIATPEVYAEMLGQAKQNSYAFPAINCTSSETVNAAIKGFADAGSDGIIQFSTGGAEFG
SGLGVKDMVTGAVALAEFTHVIAAKYPVNVALHTDHCPKDKLDSYVRPLLAISAQRVSKG
GNPLFQSHMWDGSAVPIDENLAIAQELLKAAAAAKIILEIEIGVVGGEEDGVANEINEKL
YTSPEDFEKTIEALGAGEHGKYLLAATFGNVHGVYKPGNVKLRPDILAQGQQVAAAKLGL
PADAKPFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQYAFTRPIAGHMFTNYDGVLK
VDGEVGVKKVYDPRSYLKKAEASMSQRVVQACNDLHCAGKSLTH
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| BDBM50330438 |
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| n/a |
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| Name | BDBM50330438 |
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| Synonyms: | 3-{hydroxy[(phosphonooxy)acetyl]amino}propyl dihydrogen phosphate | CHEMBL1235276 |
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| Type | Small organic molecule |
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| Emp. Form. | C5H13NO10P2 |
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| Mol. Mass. | 309.1049 |
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| SMILES | ON(CCCOP(O)(O)=O)C(=O)COP(O)(O)=O |
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| Structure | 
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