| Reaction Details |
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 | Report a problem with these data |
| Target | Fructose-bisphosphate aldolase |
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| Ligand | BDBM50330433 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_684843 (CHEMBL1286073) |
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| IC50 | 36±n/a nM |
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| Citation |  Daher, R; Coinçon, M; Fonvielle, M; Gest, PM; Guerin, ME; Jackson, M; Sygusch, J; Therisod, M Rational design, synthesis, and evaluation of new selective inhibitors of microbial class II (zinc dependent) fructose bis-phosphate aldolases. J Med Chem53:7836-42 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Fructose-bisphosphate aldolase |
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| Name: | Fructose-bisphosphate aldolase |
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| Synonyms: | Fructose-bisphosphate aldolase class II | Fructose-bisphosphate aldolase, class II |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39124.40 |
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| Organism: | Yersinia pestis |
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| Description: | ChEMBL_684843 |
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| Residue: | 359 |
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| Sequence: | MSKIFDFVKPGVITGDDVQKVFAVAKENNFALPAVNCVGTDSINAVLETAAKVRAPVIVQ
FSNGGAAFIAGKGVKTDAPQGAAILGAISGAHHVHQMAEHYGVPVILHTDHCAKKLLPWL
DGLLDAGEKHFAATGKPLFSSHMIDLSEESLEENIEICSKYLTRMSKIGMTLEIELGCTG
GEEDGVDNSHMDASSLYTQPQDVDYAYEKLNAISPRFTIAASFGNVHGVYKPGNVKLTPT
ILRDSQDYVSKKHNLPHNSLNFVFHGGSGSTAEEIKEAVSYGVVKMNIDTDTQWATWEGI
LNYYKKNEGYLQGQLGNPEGADKPNKKYYDPRVWLRAAQVTMITRLELAFKELNAIDVL
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| BDBM50330433 |
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| n/a |
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| Name | BDBM50330433 |
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| Synonyms: | 4-{hydroxy[(phosphonooxy)acetyl]amino}butyl dihydrogen phosphate | CHEMBL1236228 | N-(4-hydroxybutyl)-glycolohydroxamicacid bis-phosphate |
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| Type | Small organic molecule |
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| Emp. Form. | C6H15NO10P2 |
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| Mol. Mass. | 323.1315 |
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| SMILES | ON(CCCCOP(O)(O)=O)C(=O)COP(O)(O)=O |
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| Structure | 
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