| Reaction Details |
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 | Report a problem with these data |
| Target | Placenta growth factor |
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| Ligand | BDBM50339192 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_736105 (CHEMBL1692888) |
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| IC50 | 1000±n/a nM |
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| Citation |  Bower, KE; Lam, SN; Oates, BD; Del Rosario, JR; Corner, E; Osothprarop, TF; Kinhikar, AG; Hoye, JA; Preston, RR; Murphy, RE; Campbell, LA; Huang, H; Jimenez, J; Cao, X; Chen, G; Ainekulu, ZW; Datt, AB; Levin, NJ; Doppalapudi, VR; Pirie-Shepherd, SR; Bradshaw, C; Woodnutt, G; Lappe, RW Evolution of potent and stable placental-growth-factor-1-targeting CovX-bodies from phage display peptide discovery. J Med Chem54:1256-65 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Placenta growth factor |
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| Name: | Placenta growth factor |
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| Synonyms: | PGF | PGFL | PLGF | PLGF_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 24794.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_942634 |
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| Residue: | 221 |
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| Sequence: | MPVMRLFPCFLQLLAGLALPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVD
VVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVEL
TFSQHVRCECRHSPGRQSPDMPGDFRADAPSFLPPRRSLPMLFRMEWGCALTGSQSAVWP
SSPVPEEIPRMHPGRNGKKQQRKPLREKMKPERCGDAVPRR
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| BDBM50339192 |
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| n/a |
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| Name | BDBM50339192 |
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| Synonyms: | CHEMBL1689461 |
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| Type | Small organic molecule |
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| Emp. Form. | C99H143N23O23S3 |
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| Mol. Mass. | 2119.53 |
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| SMILES | CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)COCC(=O)Nc2ccc(CCC(=O)N3CCC3=O)cc2)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N1)C(C)C)C(N)=O |r| |
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| Structure | 
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