| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50339235 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_736202 (CHEMBL1693238) |
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| Ki | 1444±n/a nM |
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| Citation |  Mallareddy, JR; Borics, A; Keresztes, A; Kövér, KE; Tourwé, D; Tóth, G Design, synthesis, pharmacological evaluation, and structure-activity study of novel endomorphin analogues with multiple structural modifications. J Med Chem54:1462-72 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40465.04 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTAC
TPSDGPGGGAAA
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| BDBM50339235 |
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| n/a |
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| Name | BDBM50339235 |
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| Synonyms: | (1S,2R)-N-((S)-1-((2S,3S)-1-amino-1-oxo-3-phenylbutan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)cyclohexanecarboxamide | CHEMBL1689539 |
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| Type | Small organic molecule |
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| Emp. Form. | C37H44N6O5 |
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| Mol. Mass. | 652.7825 |
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| SMILES | C[C@H]([C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H]1CCCC[C@H]1NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O)c1ccccc1 |r| |
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| Structure | 
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