| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50341509 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_742114 (CHEMBL1769069) |
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| Ki | 0.59±n/a nM |
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| Citation |  Tschammer, N; Elsner, J; Goetz, A; Ehrlich, K; Schuster, S; Ruberg, M; Kühhorn, J; Thompson, D; Whistler, J; Hübner, H; Gmeiner, P Highly potent 5-aminotetrahydropyrazolopyridines: enantioselective dopamine D3 receptor binding, functional selectivity, and analysis of receptor-ligand interactions. J Med Chem54:2477-91 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
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| Type: | n/a |
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| Mol. Mass.: | 44243.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50341509 |
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| n/a |
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| Name | BDBM50341509 |
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| Synonyms: | CHEMBL1765630 | N-(4-(4-Phenylbenzoylamino)butyl)-N-propyl-5-amino-3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine |
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| Type | Small organic molecule |
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| Emp. Form. | C27H33ClN4O |
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| Mol. Mass. | 465.03 |
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| SMILES | CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCn2ncc(Cl)c2C1 |
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| Structure | 
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