| Reaction Details |
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 | Report a problem with these data |
| Target | Neurotensin receptor type 2 |
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| Ligand | BDBM50342257 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_743647 (CHEMBL1768190) |
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| Ki | 34±n/a nM |
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| Citation |  Einsiedel, J; Held, C; Hervet, M; Plomer, M; Tschammer, N; Hübner, H; Gmeiner, P Discovery of highly potent and neurotensin receptor 2 selective neurotensin mimetics. J Med Chem54:2915-23 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neurotensin receptor type 2 |
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| Name: | Neurotensin receptor type 2 |
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| Synonyms: | Levocabastine-sensitive neurotensin receptor | NT-R-2 | NTR2 | NTR2 receptor | NTR2_HUMAN | NTSR2 | Neurotensin receptor | Neurotensin receptor 2 | Neurotensin receptor type 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45404.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1281495 |
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| Residue: | 410 |
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| Sequence: | METSSPRPPRPSSNPGLSLDARLGVDTRLWAKVLFTALYALIWALGAAGNALSAHVVLKA
RAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVWFHYPWVFGDLGCRGYYFVHELCAY
ATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLVALSWAASLGLALPMAVIMGQKHEL
ETADGEPEPASRVCTVLVSRTALQVFIQVNVLVSFVLPLALTAFLNGVTVSHLLALCSQV
PSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGGQVSLVRHKDVRRIRSLQRSVQVLR
AIVVMYVICWLPYHARRLMYCYVPDDAWTDPLYNFYHYFYMVTNTLFYVSSAVTPLLYNA
VSSSFRKLFLEAVSSLCGEHHPMKRLPPKPQSPTLMDTASGFGDPPETRT
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| BDBM50342257 |
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| n/a |
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| Name | BDBM50342257 |
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| Synonyms: | (S)-2-((S)-2-((S)-3-((S)-1-((S)-5-guanidino-2-((S)-5-guanidino-2-methylpentanamido)pentanoyl)pyrrolidine-2-carboxamido)-4-(naphthalen-1-yl)but-1-en-2-ylamino)-4,4-dimethylpentanamido)-4-methylpentanoic acid | CHEMBL1766947 |
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| Type | Small organic molecule |
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| Emp. Form. | C45H71N11O6 |
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| Mol. Mass. | 862.1153 |
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| SMILES | [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]C([#6])([#6])[#6])-[#7]=[#6](-[#6])-[#6@H](-[#6]-c1cccc2ccccc12)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#6])-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](-[#8])=O |r,w:15.15| |
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| Structure | 
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