| Reaction Details |
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 | Report a problem with these data |
| Target | Neurotensin receptor type 2 |
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| Ligand | BDBM50281786 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_743647 (CHEMBL1768190) |
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| Ki | 63±n/a nM |
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| Citation |  Einsiedel, J; Held, C; Hervet, M; Plomer, M; Tschammer, N; Hübner, H; Gmeiner, P Discovery of highly potent and neurotensin receptor 2 selective neurotensin mimetics. J Med Chem54:2915-23 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neurotensin receptor type 2 |
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| Name: | Neurotensin receptor type 2 |
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| Synonyms: | Levocabastine-sensitive neurotensin receptor | NT-R-2 | NTR2 | NTR2 receptor | NTR2_HUMAN | NTSR2 | Neurotensin receptor | Neurotensin receptor 2 | Neurotensin receptor type 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45404.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1281495 |
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| Residue: | 410 |
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| Sequence: | METSSPRPPRPSSNPGLSLDARLGVDTRLWAKVLFTALYALIWALGAAGNALSAHVVLKA
RAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVWFHYPWVFGDLGCRGYYFVHELCAY
ATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLVALSWAASLGLALPMAVIMGQKHEL
ETADGEPEPASRVCTVLVSRTALQVFIQVNVLVSFVLPLALTAFLNGVTVSHLLALCSQV
PSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGGQVSLVRHKDVRRIRSLQRSVQVLR
AIVVMYVICWLPYHARRLMYCYVPDDAWTDPLYNFYHYFYMVTNTLFYVSSAVTPLLYNA
VSSSFRKLFLEAVSSLCGEHHPMKRLPPKPQSPTLMDTASGFGDPPETRT
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| BDBM50281786 |
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| n/a |
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| Name | BDBM50281786 |
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| Synonyms: | 2-{(S)-2-[2-({(S)-1-[(S)-2-((S)-2-Amino-5-guanidino-pentanoylamino)-5-guanidino-pentanoyl]-pyrrolidine-2-carbonyl}-amino)-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-4-methyl-pentanoic acid | CHEMBL172313 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H58N12O8 |
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| Mol. Mass. | 774.9106 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(O)=O |
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| Structure | 
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