| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 2 |
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| Ligand | BDBM50271187 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_751026 (CHEMBL1786811) |
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| EC50 | 2510±n/a nM |
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| Citation |  Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA Pyrimidine nucleotides with 4-alkyloxyimino and terminal tetraphosphated-ester modifications as selective agonists of the P2Y(4) receptor. J Med Chem54:4018-33 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 2 |
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| Name: | P2Y purinoceptor 2 |
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| Synonyms: | ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42299.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1455361 |
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| Residue: | 377 |
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| Sequence: | MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLC
RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS
ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR
VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK
RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC
LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR
RTESTPAGSENTKDIRL
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| BDBM50271187 |
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| n/a |
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| Name | BDBM50271187 |
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| Synonyms: | CHEMBL519835 | [dichloro({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-oxo-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl})methyl]phosphonic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C10H15Cl2N2O13P3S |
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| Mol. Mass. | 567.124 |
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| SMILES | O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)C(Cl)(Cl)P(O)(O)=O)n1ccc(=O)[nH]c1=S |r| |
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| Structure | 
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