| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dual specificity protein kinase CLK1 |
|---|
| Ligand | BDBM7266 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_749962 (CHEMBL1786939) |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  Power, DP; Lozach, O; Meijer, L; Grayson, DH; Connon, SJ Concise synthesis and CDK/GSK inhibitory activity of the missing 9-azapaullones. Bioorg Med Chem Lett20:4940-4 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Dual specificity protein kinase CLK1 |
|---|
| Name: | Dual specificity protein kinase CLK1 |
|---|
| Synonyms: | CDC-like kinase 1 | CDC-like kinase 1 (CLK1) | CDC2-like kinase 1 (CLK1) | CLK | CLK1 | CLK1_HUMAN | Dual specificity protein kinase CLK1 | Dual specificity protein kinase CLK1/CLK4 | Dual specificty protein kinase CLK1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 57322.21 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P49759 |
|---|
| Residue: | 484 |
|---|
| Sequence: | MRHSKRTYCPDWDDKDWDYGKWRSSSSHKRRKRSHSSAQENKRCKYNHSKMCDSHYLESR
SINEKDYHSRRYIDEYRNDYTQGCEPGHRQRDHESRYQNHSSKSSGRSGRSSYKSKHRIH
HSTSHRRSHGKSHRRKRTRSVEDDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECID
HKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIV
FELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSD
YTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPC
DVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWD
EHSSAGRYVSRRCKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLL
KKSI
|
|
|
|---|
| BDBM7266 |
|---|
| n/a |
|---|
| Name | BDBM7266 |
|---|
| Synonyms: | 14-bromo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaen-9-one | 9-bromopaullone | CHEMBL296586 | Kenpaullone | NSC 664704 | Paullone Analog 5 | cid_3820 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H11BrN2O |
|---|
| Mol. Mass. | 327.175 |
|---|
| SMILES | Brc1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
