| Reaction Details |
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 | Report a problem with these data |
| Target | Glycogen synthase kinase 3 |
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| Ligand | BDBM7266 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_749959 (CHEMBL1786936) |
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| IC50 | >10000±n/a nM |
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| Citation |  Power, DP; Lozach, O; Meijer, L; Grayson, DH; Connon, SJ Concise synthesis and CDK/GSK inhibitory activity of the missing 9-azapaullones. Bioorg Med Chem Lett20:4940-4 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycogen synthase kinase 3 |
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| Name: | Glycogen synthase kinase 3 |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51607.56 |
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| Organism: | Plasmodium falciparum (isolate 3D7) |
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| Description: | ChEMBL_749959 |
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| Residue: | 440 |
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| Sequence: | MKNWPIDEDINIYEEKNHTNNKNYVNNFEMSDQKDEEEYSHSSNRSEDEDEERTIDNEIN
RSPNKSYKLGNIIGNGSFGVVYEAICIDTSEQVAIKKVLQDPQYKNRELMIMKNLNHINI
IYLKDYYYTESFKKNEKNIFLNVVMEYIPQTVHKYMKYYSRNNQALPMFLVKLYSYQLCR
ALSYIHSKFICHRDLKPQNLLIDPRTHTLKLCDFGSAKNLLAGQRSVSYICSRFYRAPEL
MLGSTNYTTHIDLWSLGCIIAEMILGYPIFSGQSSVDQLVRIIQVLGTPTEDQLKEMNPN
YADIKFPDVKSKDLRKVFPKGTPDEAINLITQFLKYEPLKRLNPIEALADPFFDELRDPC
IKLPKYIDKLPELFNFCKEEIQEMSMECRRKIIPKNVYEEFLMVDENDNNIINDTISNDF
NESNLDTNNSNNKTHVIIES
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| BDBM7266 |
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| n/a |
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| Name | BDBM7266 |
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| Synonyms: | 14-bromo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaen-9-one | 9-bromopaullone | CHEMBL296586 | Kenpaullone | NSC 664704 | Paullone Analog 5 | cid_3820 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H11BrN2O |
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| Mol. Mass. | 327.175 |
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| SMILES | Brc1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1 |
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| Structure | 
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