| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50346377 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_749998 (CHEMBL1787136) |
|---|
| Ki | >10000±n/a nM |
|---|
| Citation |  Fiorino, F; Magli, E; Perissutti, E; Severino, B; Frecentese, F; Esposito, A; De Angelis, F; Incisivo, GM; Massarelli, P; Nencini, C; Di Gennaro, E; Budillon, A; Di Cintio, A; Santagada, V; Caliendo, G Synthesis of 1-naphtylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents. Eur J Med Chem46:2206-16 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 50931.60 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P61169 |
|---|
| Residue: | 444 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
|
|
|
|---|
| BDBM50346377 |
|---|
| n/a |
|---|
| Name | BDBM50346377 |
|---|
| Synonyms: | 4-[2-[4-(naphthalen)piperazin-1-yl]ethoxy]-4-aza-tricyclo [5.2.1.02,6]dec-8-ene-3,5-dione | CHEMBL1783350 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H27N3O3 |
|---|
| Mol. Mass. | 417.5002 |
|---|
| SMILES | O=C1C2C3CC(C=C3)C2C(=O)N1OCCN1CCN(CC1)c1cccc2ccccc12 |c:6| |
|---|
| Structure | 
|
|---|
Search and Browse
