Reaction Details |
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Target | Peptide deformylase, mitochondrial |
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Ligand | BDBM50349086 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_759151 (CHEMBL1811208) |
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IC50 | 65000±n/a nM |
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Citation | Antczak, C; Shum, D; Bassit, B; Frattini, MG; Li, Y; de Stanchina, E; Scheinberg, DA; Djaballah, H Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase. Bioorg Med Chem Lett21:4528-32 (2011) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Peptide deformylase, mitochondrial |
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Name: | Peptide deformylase, mitochondrial |
Synonyms: | DEFM_HUMAN | PDF | PDF1A | Peptide deformylase mitochondrial | Peptide deformylase, mitochondrial | Polypeptide deformylase |
Type: | PROTEIN |
Mol. Mass.: | 27023.25 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_154318 |
Residue: | 243 |
Sequence: | MARLWGALSLWPLWAAVPWGGAAAVGVRACSSTAAPDGVEGPALRRSYWRHLRRLVLGPP
EPPFSHVCQVGDPVLRGVAAPVERAQLGGPELQRLTQRLVQVMRRRRCVGLSAPQLGVPR
QVLALELPEALCRECPPRQRALRQMEPFPLRVFVNPSLRVLDSRLVTFPEGCESVAGFLA
CVPRFQAVQISGLDPNGEQVVWQASGWAARIIQHEMDHLQGCLFIDKMDSRTFTNVYWMK
VND
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BDBM50349086 |
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n/a |
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Name | BDBM50349086 |
Synonyms: | CHEMBL1807951 |
Type | Small organic molecule |
Emp. Form. | C16H8Br2O5 |
Mol. Mass. | 440.04 |
SMILES | COc1ccc(cc1)C(=O)c1coc2c1C(=O)C(=O)C(Br)=C2Br |c:22| |
Structure |
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