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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Bifunctional epoxide hydrolase 2 | ||
| Ligand | BDBM50351236 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_763895 (CHEMBL1819920) | ||
| IC50 | 14.8±n/a nM | ||
| Citation |  Brown, JR; North, EJ; Hurdle, JG; Morisseau, C; Scarborough, JS; Sun, D; Korduláková, J; Scherman, MS; Jones, V; Grzegorzewicz, A; Crew, RM; Jackson, M; McNeil, MR; Lee, RE The structure-activity relationship of urea derivatives as anti-tuberculosis agents. Bioorg Med Chem19:5585-95 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Bifunctional epoxide hydrolase 2 | |||
| Name: | Bifunctional epoxide hydrolase 2 | ||
| Synonyms: | Cytosolic epoxide hydrolase 2 | EBifunctional epoxide hydrolase 2 | EPHX2 | Epoxide hydratase | HYES_HUMAN | Lipid-phosphate phosphatase | Soluble epoxide hydrolase (sEH) | epoxide hydrolase 2, cytoplasmic | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 62613.07 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34913 | ||
| Residue: | 555 | ||
| Sequence: |
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| BDBM50351236 | |||
| n/a | |||
| Name | BDBM50351236 | ||
| Synonyms: | CHEMBL1818396 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H24N2O | ||
| Mol. Mass. | 284.396 | ||
| SMILES | O=C(NCc1ccccc1)NC1C2CC3CC(C2)CC1C3 |TLB:20:19:17:13.14.15,THB:10:11:17:13.14.15,20:14:11.19.18:17,15:14:11:18.16.17,15:16:11:13.20.14,(-.67,-32.55,;-.67,-34.09,;-2,-34.87,;-3.34,-34.1,;-4.67,-34.87,;-6.01,-34.1,;-7.34,-34.87,;-7.34,-36.42,;-6,-37.19,;-4.66,-36.42,;.67,-34.86,;2,-34.1,;3.19,-32.82,;4.52,-33.31,;5.91,-32.96,;5.93,-31.43,;4.53,-30.85,;3.19,-31.33,;3.49,-32.09,;3.49,-33.67,;4.91,-34.24,)| | ||
| Structure | 
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