| Reaction Details |
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 | Report a problem with these data |
| Target | Autoinducer 1 sensor kinase/phosphatase LuxN |
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| Ligand | BDBM50351502 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_765226 (CHEMBL1827779) |
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| IC50 | 2900±n/a nM |
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| Citation |  Lowery, CA; Salzameda, NT; Sawada, D; Kaufmann, GF; Janda, KD Medicinal chemistry as a conduit for the modulation of quorum sensing. J Med Chem53:7467-89 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Autoinducer 1 sensor kinase/phosphatase LuxN |
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| Name: | Autoinducer 1 sensor kinase/phosphatase LuxN |
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| Synonyms: | LUXN_VIBHA | luxN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 96099.26 |
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| Organism: | Vibrio harveyi |
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| Description: | ChEMBL_765226 |
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| Residue: | 849 |
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| Sequence: | MFDFSLEAIVYAKAISLLATVAVVMMWLFYYCYRLKQKNEVIFGTHHAAYIAYSVCIIAW
ISSNAYFHTDLLPELGASAGMFMAKFANLASFFAFAFAYYFSCQLAAEQRKGKVHRWQQG
IFVSLTVYSLFINLRPGLTVEHVDIVGPSQFIIEFGPHTSYFFIGLVSFVVLTLVNLVAM
RTNSSKLTLAKTNYMIAGILVFMLSTAVIHLGMTYFMGDFSLTWLPPALSISEMLFVGYA
LLTSRFYSVKYIAYLALSVLLVCAIFVLPLGAIFIPLTESNQWLIAIPICALIGITWQLL
YKKTSRYASFLIYGDKKTPVQQILSLEEDFKLSIDDAMRRLGKLLQIPNDKLRLVTSNYN
ETFYEEYLSSNRSVLVFDELSEELEYKVSAKRSMKALYDKMSSNNTALVMPLFGQGKSVT
HLLISPHKSNNQMFSNEEISAVQTLLTRVQSTIEADRRIRQSRALANSIAHEMRNPLAQV
QLQFEALKQHIENHAPVEQITLDIENGQAAIQRGRQLIDIILREVSDSSPEHEPIAMTSI
HKAVDQAVSHYGFENEKIIERIRLPQHTDFVAKLNETLFNFVIFNLIRNAIYYFDSYPDS
QIEISTKTGPYENTLIFRDTGPGIDETISHKIFDDFFSYQKSGGSGLGLGYCQRVMRSFG
GRIECKSKLGTFTEFHLYFPVVPNAPKADTLRTPYFNDWKQNKRSNEHKVAPNVQINNQS
PTVLIVDDKEVQRALVQMYLNQLGVNSLQANNGENAVEVFKANHVDLILMDVQMPVMNGF
DASQRIKELSPQTPIVALSGESGERELDMINKLMDGRLEKPTTLNALRHVLGNWLNKNTA
SSACEAERE
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| BDBM50351502 |
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| n/a |
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| Name | BDBM50351502 |
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| Synonyms: | CHEMBL1823947 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25N3O4S2 |
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| Mol. Mass. | 447.571 |
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| SMILES | COc1ccc(CNC(=O)C(NS(=O)(=O)c2ccc3nc(C)sc3c2)C(C)C)cc1 |
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| Structure | 
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