| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Transcriptional activator protein LasR |
|---|
| Ligand | BDBM50241433 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_765283 (CHEMBL1827922) |
|---|
| IC50 | 340±n/a nM |
|---|
| Citation |  Lowery, CA; Salzameda, NT; Sawada, D; Kaufmann, GF; Janda, KD Medicinal chemistry as a conduit for the modulation of quorum sensing. J Med Chem53:7467-89 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Transcriptional activator protein LasR |
|---|
| Name: | Transcriptional activator protein LasR |
|---|
| Synonyms: | LASR_PSEAE | lasR |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 26618.24 |
|---|
| Organism: | Pseudomonas aeruginosa |
|---|
| Description: | ChEMBL_1475312 |
|---|
| Residue: | 239 |
|---|
| Sequence: | MALVDGFLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAW
REHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHG
ARGELGALSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAFEHPVSKPVVLTSR
EKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMAVNLGLITL
|
|
|
|---|
| BDBM50241433 |
|---|
| n/a |
|---|
| Name | BDBM50241433 |
|---|
| Synonyms: | (S)-3-(4-bromophenyl)-N-(2-oxo-tetrahydrofuran-3-yl)propanamide | (S)-3-(4-bromophenyl)-N-(2-oxotetrahydrofuran-3-yl)propanamide | CHEMBL264944 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H14BrNO3 |
|---|
| Mol. Mass. | 312.159 |
|---|
| SMILES | Brc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
