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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Histamine H3 receptor | ||
| Ligand | BDBM50352079 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_766550 (CHEMBL1827031) | ||
| Ki | 0.64±n/a nM | ||
| Citation |  Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Novel and highly potent histamine H3 receptor ligands. Part 2: exploring the cyclohexylamine-based series. Bioorg Med Chem Lett21:5384-8 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Histamine H3 receptor | |||
| Name: | Histamine H3 receptor | ||
| Synonyms: | G-protein coupled receptor 97 | GPCR97 | HH3R | HISTAMINE H3 | HRH3 | HRH3_HUMAN | Histamine H3 receptor (H3) | Histamine H3L | Histamine receptor (H3 and H4) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 48691.47 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Binding assays were using CHO cells stably expressing hH3R receptors. | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50352079 | |||
| n/a | |||
| Name | BDBM50352079 | ||
| Synonyms: | CHEMBL1824249 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H40N2O | ||
| Mol. Mass. | 372.5872 | ||
| SMILES | CCCCN[C@H]1CC[C@@H](CC1)c1ccc(OCCCN2CCCCC2)cc1 |r,wU:5.4,wD:8.11,(39.04,-38.4,;37.5,-38.39,;36.72,-39.72,;35.18,-39.7,;34.4,-41.03,;32.86,-41.01,;32.07,-42.34,;30.54,-42.33,;29.78,-40.99,;30.55,-39.66,;32.09,-39.67,;28.23,-40.97,;27.45,-42.3,;25.92,-42.3,;25.16,-40.95,;23.62,-40.95,;22.85,-42.28,;21.31,-42.28,;20.54,-40.95,;19,-40.95,;18.23,-42.27,;16.69,-42.27,;15.92,-40.95,;16.69,-39.61,;18.23,-39.61,;25.92,-39.63,;27.47,-39.64,)| | ||
| Structure | 
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