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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Histamine H3 receptor | ||
| Ligand | BDBM50352091 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_766550 (CHEMBL1827031) | ||
| Ki | 0.67±n/a nM | ||
| Citation |  Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Novel and highly potent histamine H3 receptor ligands. Part 2: exploring the cyclohexylamine-based series. Bioorg Med Chem Lett21:5384-8 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Histamine H3 receptor | |||
| Name: | Histamine H3 receptor | ||
| Synonyms: | G-protein coupled receptor 97 | GPCR97 | HH3R | HISTAMINE H3 | HRH3 | HRH3_HUMAN | Histamine H3 receptor (H3) | Histamine H3L | Histamine receptor (H3 and H4) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 48691.47 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Binding assays were using CHO cells stably expressing hH3R receptors. | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50352091 | |||
| n/a | |||
| Name | BDBM50352091 | ||
| Synonyms: | CHEMBL1824240 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H38N2O2 | ||
| Mol. Mass. | 386.5707 | ||
| SMILES | C(COc1ccc(cc1)[C@@H]1CC[C@@H](CC1)N1CCOCC1)CN1CCCCC1 |r,wU:9.9,12.16,(-3.9,-23.3,;-2.36,-23.3,;-1.59,-21.97,;-.05,-21.97,;.71,-23.31,;2.25,-23.32,;3.03,-21.99,;2.26,-20.65,;.71,-20.64,;4.57,-22,;5.33,-23.34,;6.86,-23.36,;7.65,-22.03,;6.89,-20.69,;5.34,-20.67,;9.19,-22.04,;9.94,-23.38,;11.47,-23.4,;12.26,-22.08,;11.5,-20.74,;9.96,-20.72,;-4.67,-21.96,;-6.21,-21.96,;-6.98,-23.29,;-8.52,-23.29,;-9.29,-21.96,;-8.52,-20.63,;-6.98,-20.63,)| | ||
| Structure | 
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