| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
|---|
| Ligand | BDBM50353855 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_769366 (CHEMBL1833372) |
|---|
| Ki | >10000±n/a nM |
|---|
| Citation |  Mésangeau, C; Amata, E; Alsharif, W; Seminerio, MJ; Robson, MJ; Matsumoto, RR; Poupaert, JH; McCurdy, CR Synthesis and pharmacological evaluation of indole-based sigma receptor ligands. Eur J Med Chem46:5154-61 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(1A) dopamine receptor |
|---|
| Name: | D(1A) dopamine receptor |
|---|
| Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 49303.43 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21728 |
|---|
| Residue: | 446 |
|---|
| Sequence: | MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLA
ETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN
CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIET
VSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
|
|
|
|---|
| BDBM50353855 |
|---|
| n/a |
|---|
| Name | BDBM50353855 |
|---|
| Synonyms: | CHEMBL1831166 | US9604926, Compound CM-361 | US9724435, Compound CM-361 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H31FN2O2 |
|---|
| Mol. Mass. | 458.567 |
|---|
| SMILES | COc1cc2CCN(CCCCn3cc(-c4ccc(F)cc4)c4ccccc34)Cc2cc1OC |
|---|
| Structure | 
|
|---|
Search and Browse
