Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetSigma non-opioid intracellular receptor 1
LigandBDBM50353859
Substrate/Competitorn/a
Meas. Tech.ChEMBL_769360 (CHEMBL1833366)
Ki 5.33±n/a nM
Citation Mésangeau, CAmata, EAlsharif, WSeminerio, MJRobson, MJMatsumoto, RRPoupaert, JHMcCurdy, CR Synthesis and pharmacological evaluation of indole-based sigma receptor ligands. Eur J Med Chem46:5154-61 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma non-opioid intracellular receptor 1
Synonyms:Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:Enzyme Catalytic Domain
Mol. Mass.:25266.54
Organism:RAT
Description:Q9R0C9
Residue:223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50353859
n/a
NameBDBM50353859
Synonyms:CHEMBL1831158
TypeSmall organic molecule
Emp. Form.C24H35N3O
Mol. Mass.381.5542
SMILESCC(=O)c1ccc2n(CCCCN3CCN(CC3)C3CCCCC3)ccc2c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: