| Reaction Details |
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 | Report a problem with these data |
| Target | Acrosin |
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| Ligand | BDBM50354865 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_772454 (CHEMBL1839245) |
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| IC50 | 14000000±n/a nM |
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| Citation |  Qi, J; Zhu, J; Liu, X; Ding, L; Zheng, C; Han, G; Lv, J; Zhou, Y Synthesis and acrosin inhibitory activities of substituted ethyl 5-(4-aminophenyl)-1H-pyrazole-3-carboxylate derivatives. Bioorg Med Chem Lett21:5822-5 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acrosin |
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| Name: | Acrosin |
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| Synonyms: | ACR | ACRO_HUMAN | ACRS |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45865.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1365286 |
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| Residue: | 421 |
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| Sequence: | MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSL
QIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPL
QERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVA
GWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDS
GGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSA
TPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPASP
LPPPPPPPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGKNHYDMETTELPELTST
S
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| BDBM50354865 |
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| n/a |
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| Name | BDBM50354865 |
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| Synonyms: | CHEMBL1834546 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H17N3O3 |
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| Mol. Mass. | 287.3138 |
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| SMILES | CCOC(=O)c1cc(n[nH]1)-c1ccc(NC(=O)CC)cc1 |
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| Structure | 
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