| Reaction Details |
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 | Report a problem with these data |
| Target | Substance-K receptor |
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| Ligand | BDBM50357013 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_788340 (CHEMBL1918021) |
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| Ki | 100000±n/a nM |
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| Citation |  Singh, GS; Mmatli, EE Recent progress in synthesis and bioactivity studies of indolizines. Eur J Med Chem46:5237-57 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Substance-K receptor |
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| Name: | Substance-K receptor |
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| Synonyms: | NK-2 receptor | NK-2R | NK2R | NK2R_HUMAN | NKNAR | Neurokinin 2 receptor | Neurokinin A receptor | Neurokinin NK2 | Neurokinin-2 (NK-2) | Neuromedin-2 receptor (NK-2R) | SKR | TAC2R | TACR2 | Tachykinin receptor 2 | Tachykinin receptor 2 (NK2) | hnk-3 |
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| Type: | Protein |
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| Mol. Mass.: | 44455.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21452 |
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| Residue: | 398 |
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| Sequence: | MGTCDIVTEANISSGPESNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILA
HRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVS
IYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGATK
CVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLR
HLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSST
MYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLFMA
GDTAPSEATSGEAGRPQDGSGLWFGYGLLAPTKTHVEI
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| BDBM50357013 |
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| n/a |
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| Name | BDBM50357013 |
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| Synonyms: | CHEMBL1916635 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H41N5O7 |
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| Mol. Mass. | 691.7721 |
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| SMILES | COC(=O)C1=C2CCC(N2C(=O)C(C1)NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCc1c[nH]c2ccccc12)C(=O)N(C)Cc1ccccc1 |r,c:4| |
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| Structure | 
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