| Reaction Details |
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 | Report a problem with these data |
| Target | Proton-coupled amino acid transporter 1 |
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| Ligand | BDBM50219348 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_788189 (CHEMBL1919336) |
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| Ki | 100000000±n/a nM |
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| Citation |  Thondorf, I; Voigt, V; Schäfer, S; Gebauer, S; Zebisch, K; Laug, L; Brandsch, M Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1). Bioorg Med Chem19:6409-18 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Proton-coupled amino acid transporter 1 |
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| Name: | Proton-coupled amino acid transporter 1 |
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| Synonyms: | PAT1 | Proton/amino acid transporter 1 | S36A1_HUMAN | SLC36A1 | Solute carrier family 36 member 1 | hPAT1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53078.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_788189 |
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| Residue: | 476 |
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| Sequence: | MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN
IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV
MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC
HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIV
QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT
ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP
FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE
VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI
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| BDBM50219348 |
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| n/a |
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| Name | BDBM50219348 |
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| Synonyms: | (2S)-2-amino-4-methylpentanoic acid | (S)-(+)-leucine | (S)-leucine | CHEMBL291962 | L-Leucin | L-Leuzin | L-leucine |
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| Type | Small organic molecule |
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| Emp. Form. | C6H13NO2 |
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| Mol. Mass. | 131.1729 |
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| SMILES | CC(C)C[C@H](N)C(O)=O |
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| Structure | 
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