| Reaction Details |
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 | Report a problem with these data |
| Target | Toll-like receptor 2 |
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| Ligand | BDBM50358554 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_790131 (CHEMBL1926410) |
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| EC50 | >1000±n/a nM |
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| Citation |  Agnihotri, G; Crall, BM; Lewis, TC; Day, TP; Balakrishna, R; Warshakoon, HJ; Malladi, SS; David, SA Structure-activity relationships in toll-like receptor 2-agonists leading to simplified monoacyl lipopeptides. J Med Chem54:8148-60 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Toll-like receptor 2 |
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| Name: | Toll-like receptor 2 |
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| Synonyms: | TIL4 | TLR2 | TLR2_HUMAN | Toll-like receptor 2 | Toll-like receptor 2 (TLR2) |
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| Type: | Protein |
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| Mol. Mass.: | 89837.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O60603 |
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| Residue: | 784 |
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| Sequence: | MPHTLWMVWVLGVIISLSKEESSNQASLSCDRNGICKGSSGSLNSIPSGLTEAVKSLDLS
NNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSSWF
KPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELE
IDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTDLDTFHFS
ELSTGETNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFDDCTLNGVGNFRASDN
DRVIDPGKVETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPCLLSQHLK
SLEYLDLSENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNIDI
SKNSFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSLNLPQLK
ELYISRNKLMTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCE
FLSFTQEQQALAKVLIDWPANYLCDSPSHVRGQQVQDVRLSVSECHRTALVSGMCCALFL
LILLTGVLCHRFHGLWYMKMMWAWLQAKRKPRKAPSRNICYDAFVSYSERDAYWVENLMV
QELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTVFVLSENFVKSEWCKYELDFS
HFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPMDEAQREGFWVNLRA
AIKS
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| BDBM50358554 |
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| n/a |
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| Name | BDBM50358554 |
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| Synonyms: | CHEMBL1923553 |
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| Type | Small organic molecule |
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| Emp. Form. | C44H84N2O8S |
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| Mol. Mass. | 801.211 |
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| SMILES | CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC(C)(C)[C@@H](N)C(=O)N[C@@H](CO)C(=O)OC)OC(=O)CCCCCCCCCCCCCCC |r| |
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| Structure | 
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