| Reaction Details |
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 | Report a problem with these data |
| Target | Galanin receptor type 2 |
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| Ligand | BDBM50358676 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_789439 (CHEMBL1924415) |
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| IC50 | 380±n/a nM |
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| Citation |  Sagi, VN; Liu, T; Lu, X; Bartfai, T; Roberts, E Synthesis and biological evaluation of novel pyrimidine derivatives as sub-micromolar affinity ligands of GalR2. Bioorg Med Chem Lett21:7210-5 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Galanin receptor type 2 |
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| Name: | Galanin receptor type 2 |
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| Synonyms: | GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2). |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41724.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Galanin R2 GALR2 HUMAN::O43603 |
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| Residue: | 387 |
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| Sequence: | MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTT
NLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVS
LDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWS
APRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILI
VAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFR
KGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQ
PCILEPCPGPSWQGPKAGDSILTVDVA
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| BDBM50358676 |
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| n/a |
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| Name | BDBM50358676 |
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| Synonyms: | CHEMBL1922006 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H24F3N5O2 |
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| Mol. Mass. | 459.4642 |
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| SMILES | COc1ccc(Nc2nc(Nc3cccc(OC(F)(F)F)c3)cc(n2)N2CCCCC2)cc1 |
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| Structure | 
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