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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | C-C chemokine receptor type 2 | ||
| Ligand | BDBM50359101 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_789638 (CHEMBL1924723) | ||
| IC50 | 64±n/a nM | ||
| Citation |  Lanter, JC; Markotan, TP; Zhang, X; Subasinghe, N; Kang, FA; Hou, C; Singer, M; Opas, E; McKenney, S; Crysler, C; Johnson, D; Molloy, CJ; Sui, Z The discovery of novel cyclohexylamide CCR2 antagonists. Bioorg Med Chem Lett21:7496-501 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| C-C chemokine receptor type 2 | |||
| Name: | C-C chemokine receptor type 2 | ||
| Synonyms: | C-C chemokine receptor type 2 (CCR2) | CCR2 | CCR2_HUMAN | CMKBR2 | Chemoattractant Cytokine Receptor 2 (CCR2) | Chemokine Receptor Type 2b (CCR2b) | Monocyte chemotactic protein-1 (MCP-1) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 41932.32 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41597 | ||
| Residue: | 374 | ||
| Sequence: |
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| BDBM50359101 | |||
| n/a | |||
| Name | BDBM50359101 | ||
| Synonyms: | CHEMBL1922814 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H35FN4O2 | ||
| Mol. Mass. | 502.6229 | ||
| SMILES | NC(=O)C(NC1CCC(CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)\C=C\c1cccc(F)c1 |(41.98,-9.05,;43.32,-9.83,;44.65,-9.06,;43.31,-11.37,;41.97,-12.13,;41.97,-13.67,;40.63,-14.44,;40.63,-15.97,;41.96,-16.75,;43.3,-15.98,;43.3,-14.43,;41.96,-18.29,;40.71,-19.2,;41.19,-20.66,;42.73,-20.65,;43.76,-21.79,;45.26,-21.47,;45.73,-20,;44.7,-18.86,;43.2,-19.19,;44.64,-12.14,;44.63,-13.68,;45.95,-14.46,;47.29,-13.7,;47.3,-12.16,;45.97,-11.37,;48.62,-14.48,;48.61,-16.02,;49.96,-13.71,;51.29,-14.49,;52.63,-13.73,;52.63,-12.2,;53.96,-11.44,;55.3,-12.22,;55.29,-13.76,;56.61,-14.54,;53.95,-14.52,)| | ||
| Structure | 
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