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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | C-C chemokine receptor type 2 | ||
| Ligand | BDBM50359105 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_789638 (CHEMBL1924723) | ||
| IC50 | 9572±n/a nM | ||
| Citation |  Lanter, JC; Markotan, TP; Zhang, X; Subasinghe, N; Kang, FA; Hou, C; Singer, M; Opas, E; McKenney, S; Crysler, C; Johnson, D; Molloy, CJ; Sui, Z The discovery of novel cyclohexylamide CCR2 antagonists. Bioorg Med Chem Lett21:7496-501 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| C-C chemokine receptor type 2 | |||
| Name: | C-C chemokine receptor type 2 | ||
| Synonyms: | C-C chemokine receptor type 2 (CCR2) | CCR2 | CCR2_HUMAN | CMKBR2 | Chemoattractant Cytokine Receptor 2 (CCR2) | Chemokine Receptor Type 2b (CCR2b) | Monocyte chemotactic protein-1 (MCP-1) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 41932.32 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41597 | ||
| Residue: | 374 | ||
| Sequence: |
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| BDBM50359105 | |||
| n/a | |||
| Name | BDBM50359105 | ||
| Synonyms: | CHEMBL1922811 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H35N5O2 | ||
| Mol. Mass. | 473.6098 | ||
| SMILES | NC(=O)C(NC1CCC(CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)Nc1ccccc1 |(-7.99,-9.65,;-6.66,-10.43,;-5.32,-9.66,;-6.66,-11.97,;-8,-12.73,;-8,-14.27,;-9.34,-15.03,;-9.34,-16.57,;-8.01,-17.34,;-6.67,-16.58,;-6.67,-15.03,;-8.02,-18.88,;-9.26,-19.79,;-8.78,-21.26,;-7.24,-21.25,;-6.22,-22.39,;-4.71,-22.07,;-4.24,-20.6,;-5.27,-19.46,;-6.77,-19.79,;-5.33,-12.74,;-5.34,-14.28,;-4.02,-15.06,;-2.68,-14.3,;-2.67,-12.75,;-4,-11.97,;-1.35,-15.07,;-1.36,-16.61,;-.01,-14.31,;1.32,-15.09,;1.3,-16.63,;2.63,-17.41,;3.97,-16.65,;3.97,-15.1,;2.64,-14.33,)| | ||
| Structure | 
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