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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | C-C chemokine receptor type 2 | ||
| Ligand | BDBM50359106 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_789638 (CHEMBL1924723) | ||
| IC50 | >25000±n/a nM | ||
| Citation |  Lanter, JC; Markotan, TP; Zhang, X; Subasinghe, N; Kang, FA; Hou, C; Singer, M; Opas, E; McKenney, S; Crysler, C; Johnson, D; Molloy, CJ; Sui, Z The discovery of novel cyclohexylamide CCR2 antagonists. Bioorg Med Chem Lett21:7496-501 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| C-C chemokine receptor type 2 | |||
| Name: | C-C chemokine receptor type 2 | ||
| Synonyms: | C-C chemokine receptor type 2 (CCR2) | CCR2 | CCR2_HUMAN | CMKBR2 | Chemoattractant Cytokine Receptor 2 (CCR2) | Chemokine Receptor Type 2b (CCR2b) | Monocyte chemotactic protein-1 (MCP-1) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 41932.32 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41597 | ||
| Residue: | 374 | ||
| Sequence: |
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| BDBM50359106 | |||
| n/a | |||
| Name | BDBM50359106 | ||
| Synonyms: | CHEMBL1922809 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C29H36N4O2 | ||
| Mol. Mass. | 472.6217 | ||
| SMILES | NC(=O)C(NC1CCC(CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)Cc1ccccc1 |(43.31,5.77,;44.65,5,;45.98,5.76,;44.64,3.46,;43.3,2.69,;43.3,1.15,;41.96,.39,;41.96,-1.14,;43.29,-1.92,;44.63,-1.15,;44.63,.39,;43.29,-3.46,;42.04,-4.37,;42.52,-5.83,;44.06,-5.82,;45.09,-6.96,;46.59,-6.64,;47.06,-5.17,;46.03,-4.04,;44.53,-4.36,;45.97,2.68,;45.96,1.14,;47.28,.37,;48.62,1.13,;48.63,2.67,;47.3,3.45,;49.95,.35,;49.94,-1.19,;51.29,1.11,;52.62,.33,;52.6,-1.21,;53.93,-1.99,;55.27,-1.23,;55.27,.32,;53.95,1.09,)| | ||
| Structure | 
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