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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | C-C chemokine receptor type 2 | ||
| Ligand | BDBM50359107 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_789638 (CHEMBL1924723) | ||
| IC50 | 1300±n/a nM | ||
| Citation |  Lanter, JC; Markotan, TP; Zhang, X; Subasinghe, N; Kang, FA; Hou, C; Singer, M; Opas, E; McKenney, S; Crysler, C; Johnson, D; Molloy, CJ; Sui, Z The discovery of novel cyclohexylamide CCR2 antagonists. Bioorg Med Chem Lett21:7496-501 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| C-C chemokine receptor type 2 | |||
| Name: | C-C chemokine receptor type 2 | ||
| Synonyms: | C-C chemokine receptor type 2 (CCR2) | CCR2 | CCR2_HUMAN | CMKBR2 | Chemoattractant Cytokine Receptor 2 (CCR2) | Chemokine Receptor Type 2b (CCR2b) | Monocyte chemotactic protein-1 (MCP-1) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 41932.32 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41597 | ||
| Residue: | 374 | ||
| Sequence: |
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| BDBM50359107 | |||
| n/a | |||
| Name | BDBM50359107 | ||
| Synonyms: | CHEMBL1922808 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C31H38N4O2 | ||
| Mol. Mass. | 498.659 | ||
| SMILES | NC(=O)C(NC1CCC(CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)C1CC1c1ccccc1 |(27.7,6.46,;29.03,5.68,;30.36,6.45,;29.02,4.14,;27.69,3.38,;27.69,1.84,;26.35,1.07,;26.34,-.46,;27.67,-1.24,;29.01,-.47,;29.02,1.08,;27.67,-2.78,;26.42,-3.69,;26.91,-5.15,;28.44,-5.14,;29.47,-6.28,;30.97,-5.96,;31.44,-4.49,;30.41,-3.36,;28.92,-3.68,;30.35,3.37,;30.34,1.83,;31.66,1.05,;33,1.81,;33.01,3.35,;31.68,4.14,;34.33,1.03,;34.32,-.51,;35.67,1.79,;36.45,3.13,;37.21,1.79,;38.54,1.01,;38.52,-.53,;39.85,-1.31,;41.19,-.55,;41.2,1,;39.87,1.77,)| | ||
| Structure | 
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