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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | C-C chemokine receptor type 2 | ||
| Ligand | BDBM50359109 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_789638 (CHEMBL1924723) | ||
| IC50 | 190±n/a nM | ||
| Citation |  Lanter, JC; Markotan, TP; Zhang, X; Subasinghe, N; Kang, FA; Hou, C; Singer, M; Opas, E; McKenney, S; Crysler, C; Johnson, D; Molloy, CJ; Sui, Z The discovery of novel cyclohexylamide CCR2 antagonists. Bioorg Med Chem Lett21:7496-501 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| C-C chemokine receptor type 2 | |||
| Name: | C-C chemokine receptor type 2 | ||
| Synonyms: | C-C chemokine receptor type 2 (CCR2) | CCR2 | CCR2_HUMAN | CMKBR2 | Chemoattractant Cytokine Receptor 2 (CCR2) | Chemokine Receptor Type 2b (CCR2b) | Monocyte chemotactic protein-1 (MCP-1) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 41932.32 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41597 | ||
| Residue: | 374 | ||
| Sequence: |
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| BDBM50359109 | |||
| n/a | |||
| Name | BDBM50359109 | ||
| Synonyms: | CHEMBL1922806 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H36N4O2 | ||
| Mol. Mass. | 484.6324 | ||
| SMILES | NC(=O)C(NC1CCC(CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)\C=C\c1ccccc1 |(-8.41,5.29,;-7.08,4.51,;-5.74,5.28,;-7.08,2.97,;-8.42,2.21,;-8.42,.67,;-9.76,-.09,;-9.76,-1.63,;-8.43,-2.4,;-7.09,-1.64,;-7.09,-.09,;-8.44,-3.94,;-9.68,-4.85,;-9.2,-6.32,;-7.66,-6.31,;-6.64,-7.45,;-5.13,-7.13,;-4.66,-5.66,;-5.69,-4.52,;-7.19,-4.84,;-5.75,2.2,;-5.76,.66,;-4.44,-.11,;-3.1,.65,;-3.09,2.19,;-4.42,2.97,;-1.77,-.13,;-1.78,-1.67,;-.43,.63,;.9,-.15,;2.23,.61,;3.56,-.17,;4.89,.59,;4.91,2.13,;3.57,2.91,;2.24,2.14,)| | ||
| Structure | 
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