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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | C-C chemokine receptor type 2 | ||
| Ligand | BDBM50359121 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_789638 (CHEMBL1924723) | ||
| IC50 | 2200±n/a nM | ||
| Citation |  Lanter, JC; Markotan, TP; Zhang, X; Subasinghe, N; Kang, FA; Hou, C; Singer, M; Opas, E; McKenney, S; Crysler, C; Johnson, D; Molloy, CJ; Sui, Z The discovery of novel cyclohexylamide CCR2 antagonists. Bioorg Med Chem Lett21:7496-501 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| C-C chemokine receptor type 2 | |||
| Name: | C-C chemokine receptor type 2 | ||
| Synonyms: | C-C chemokine receptor type 2 (CCR2) | CCR2 | CCR2_HUMAN | CMKBR2 | Chemoattractant Cytokine Receptor 2 (CCR2) | Chemokine Receptor Type 2b (CCR2b) | Monocyte chemotactic protein-1 (MCP-1) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 41932.32 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41597 | ||
| Residue: | 374 | ||
| Sequence: |
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| BDBM50359121 | |||
| n/a | |||
| Name | BDBM50359121 | ||
| Synonyms: | CHEMBL1922795 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C29H32F3N5O2 | ||
| Mol. Mass. | 539.5919 | ||
| SMILES | NC(=O)C(NC1CCC(CC1)c1c[nH]c2cnccc12)C1CCN(CC1)C(=O)\C=C\c1cc(F)c(F)c(F)c1 |(32.32,5.53,;33.66,4.76,;34.99,5.52,;33.65,3.22,;32.31,2.45,;32.31,.91,;30.97,.15,;30.97,-1.39,;32.3,-2.16,;33.64,-1.39,;33.64,.15,;32.3,-3.7,;31.05,-4.61,;31.53,-6.08,;33.07,-6.07,;34.1,-7.21,;35.6,-6.89,;36.07,-5.41,;35.04,-4.28,;33.54,-4.6,;34.98,2.44,;34.97,.9,;36.29,.13,;37.63,.89,;37.64,2.43,;36.31,3.21,;38.96,.11,;38.95,-1.43,;40.3,.87,;41.63,.09,;42.97,.85,;42.97,2.38,;44.3,3.15,;44.3,4.69,;45.64,2.37,;46.98,3.13,;45.63,.83,;46.95,.05,;44.29,.07,)| | ||
| Structure | 
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