| Reaction Details |
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 | Report a problem with these data |
| Target | Calcium/calmodulin-dependent protein kinase type II subunit delta |
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| Ligand | BDBM50361934 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_799032 (CHEMBL1941891) |
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| IC50 | 154±n/a nM |
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| Citation |  Shahin, R; Taha, MO Elaborate ligand-based modeling and subsequent synthetic exploration unveil new nanomolar Ca2+/calmodulin-dependent protein kinase II inhibitory leads. Bioorg Med Chem20:377-400 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcium/calmodulin-dependent protein kinase type II subunit delta |
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| Name: | Calcium/calmodulin-dependent protein kinase type II subunit delta |
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| Synonyms: | CAMK2D | CAMKD | CaM kinase II | CaM kinase II delta | CaMK-II subunit delta | Calcium/calmodulin-dependent protein kinase type II subunit delta | Calcium/calmodulin-dependent protein kinase type II subunit delta (CAMK2D) | Calcium/calmodulin-dependent protein kinase type II subunit delta (CaMKII subunit delta) | KCC2D_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 56419.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13557 |
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| Residue: | 499 |
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| Sequence: | MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT
VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL
KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA
INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH
LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIKPP
CIPNGKENFSGGTSLWQNI
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| BDBM50361934 |
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| n/a |
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| Name | BDBM50361934 |
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| Synonyms: | CHEMBL1939328 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H35N9O2 |
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| Mol. Mass. | 457.5724 |
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| SMILES | CCCCCNc1nc(Nc2ccc(cc2)[N+]([O-])=O)nc(n1)N1CCN(CCN(C)C)CC1 |
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| Structure | 
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