| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM50403242 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_34647 (CHEMBL648938) |
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| IC50 | 2±n/a nM |
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| Citation |  Dorsch, D; Mederski, WW; Beier, N; Lues, I; Minck, K; Schelling, P (6-oxo-3-pyridazinyl)-benzimidazoles as potent angiotensin II receptor antagonists Bioorg Med Chem Lett4:1297-1302 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1_RABIT | ANGIOTENSIN AT1 | Angiotensin II receptor | Angiotensin II type 1a (AT-1a) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41009.15 |
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| Organism: | RABBIT |
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| Description: | ANGIOTENSIN AT1 AGTR1 RABBIT::P34976 |
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| Residue: | 359 |
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| Sequence: | MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
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| BDBM50403242 |
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| n/a |
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| Name | BDBM50403242 |
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| Synonyms: | CHEMBL2079790 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H32N9O2 |
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| Mol. Mass. | 586.6668 |
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| SMILES | CC1CC(=O)N(CC(=O)N(C)C)N=C1c1ccc2nc(C3CC3)n(Cc3ccc(cc3)-c3ccccc3-c3nn[n-]n3)c2c1 |c:12| |
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| Structure | 
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