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TargetAdenosine receptor A1
LigandBDBM50069320
Substrate/Competitorn/a
Meas. Tech.ChEMBL_27425 (CHEMBL646669)
EC50 869±n/a nM
Citation Camp, D; Green, JM; Kaiser, SM; Moni, RW; Townsend-Nicholson, A; Schofield, PR; Quinn, RJ Diimidazo[1,2-c:4',5'-e]pyrimidines: adenosine agonist activity demonstrated by microphysiometry. Bioorg Med Chem Lett8:691-4 (1999) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A1
Name:Adenosine receptor A1
Synonyms:A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:36520.92
Organism:Homo sapiens (Human)
Description:P30542
Residue:326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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  Blast E-value cutoff:
BDBM50069320
n/a
NameBDBM50069320
Synonyms:(2S,3S,4S,5S)-2-(6-Amino-purin-9-yl)-5-(1-methyl-1-phenyl-ethoxymethyl)-tetrahydro-furan-3,4-diol | CHEMBL162752
TypeSmall organic molecule
Emp. Form.C19H23N5O4
Mol. Mass.385.417
SMILESCC(C)(OC[C@@H]1O[C@@H]([C@@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)c1ccccc1
Structure
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