| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50366623 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_92406 (CHEMBL701400) |
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| Ki | 3911±n/a nM |
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| Citation |  Coop, A; Pinto, J; Wang, L; McCullough, K; Rothman, RB; Dersch, C; Jacobson, AE; Rice, KC Delta opioid binding selectivity of 3-ether analogs of naltrindole. Bioorg Med Chem Lett9:3435-8 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42744.99 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | P41144 |
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| Residue: | 380 |
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| Sequence: | MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
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| BDBM50366623 |
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| n/a |
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| Name | BDBM50366623 |
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| Synonyms: | CHEMBL1744389 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H28N2O3 |
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| Mol. Mass. | 428.5228 |
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| SMILES | COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45C(Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O |r| |
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| Structure | 
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