| Reaction Details |
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 | Report a problem with these data |
| Target | Transporter |
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| Ligand | BDBM50090498 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_143128 |
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| Ki | 3140±n/a nM |
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| Citation |  Tamiz, AP; Smith, MP; Enyedy, I; Flippen-Anderson, J; Zhang, M; Johnson, KM; Kozikowski, AP Synthesis and biological evaluation of 1-azabicyclo-[3.2.1]octanes: new dopamine transporter inhibitors. Bioorg Med Chem Lett10:1681-6 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Transporter |
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| Name: | Transporter |
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| Synonyms: | Monoamine transporters; Norepininephrine & dopamine | Norepinephrine Monoamine transporters |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66787.87 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1463061 |
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| Residue: | 597 |
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| Sequence: | MVTRTRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLF
YMELALGQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLN
LPWTNCGHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDI
GLPQWQLLLCLMVVIVVLYVSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNG
INAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTIN
CVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFL
MLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLT
LLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLL
FVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAY
GITPENEHHLLALEIELSSLQSFVITSCPIDPLLSSFLFISCQKTLVFKKSGPAPLI
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| BDBM50090498 |
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| n/a |
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| Name | BDBM50090498 |
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| Synonyms: | 4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxylic acid 3,3-diphenyl-propyl ester | CHEMBL43713 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H30ClNO2 |
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| Mol. Mass. | 447.996 |
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| SMILES | CN1CCC(C(C1)C(=O)OCCC(c1ccccc1)c1ccccc1)c1ccc(Cl)cc1 |
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| Structure | 
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