| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
|---|
| Ligand | BDBM50087258 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_45063 |
|---|
| Ki | 3±n/a nM |
|---|
| Citation |  Renzi, G; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: topical sulfonamide antiglaucoma agents incorporating secondary amine moieties. Bioorg Med Chem Lett10:673-6 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 2 |
|---|
| Name: | Carbonic anhydrase 2 |
|---|
| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29250.71 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P00918 |
|---|
| Residue: | 260 |
|---|
| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
|
|
|
|---|
| BDBM50087258 |
|---|
| n/a |
|---|
| Name | BDBM50087258 |
|---|
| Synonyms: | 4-[(7-Chloro-2-oxo-2H-chromen-4-ylmethyl)-ethyl-amino]-2-methyl-1,1-dioxo-2,3,4,7-tetrahydro-1H-1lambda*6*-cyclopenta[b]thiopyran-6-sulfonic acid amide | CHEMBL345585 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H18ClN3O6S2 |
|---|
| Mol. Mass. | 519.978 |
|---|
| SMILES | NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(NCc3cc(=O)oc4cc(Cl)ccc34)cc2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
