| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 4 |
|---|
| Ligand | BDBM50087256 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_45274 |
|---|
| Ki | 30±n/a nM |
|---|
| Citation |  Renzi, G; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: topical sulfonamide antiglaucoma agents incorporating secondary amine moieties. Bioorg Med Chem Lett10:673-6 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 4 |
|---|
| Name: | Carbonic anhydrase 4 |
|---|
| Synonyms: | CA-IV | CA4 | CAH4_BOVIN | Carbonate dehydratase IV | Carbonic Anhydrase IV | Carbonic anhydrase | Carbonic anhydrase 4 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 35152.74 |
|---|
| Organism: | Bos taurus (bovine) |
|---|
| Description: | Bovine isozyme, isolated from lung microsomes |
|---|
| Residue: | 312 |
|---|
| Sequence: | MRLLLALLVLAAAPPQARAASHWCYQIQVKPSNYTCLEPDEWEGSCQNNRQSPVNIVTAK
TQLDPNLGRFSFSGYNMKHQWVVQNNGHTVMVLLENKPSIAGGGLSTRYQATQLHLHWSR
AMDRGSEHSFDGERFAMEMHIVHEKEKGLSGNASQNQFAEDEIAVLAFMVEDGSKNVNFQ
PLVEALSDIPRPNMNTTMKEGVSLFDLLPEEESLRHYFRYLGSLTTPTCDEKVVWTVFQK
PIQLHRDQILAFSQKLFYDDQQKVNMTDNVRPVQSLGQRQVFRSGAPGLLLAQPLPTLLA
PVLACLTVGFLR
|
|
|
|---|
| BDBM50087256 |
|---|
| n/a |
|---|
| Name | BDBM50087256 |
|---|
| Synonyms: | 3-[4-(7-chloro-2-oxo-2H-4-chromenylmethylamino)phenylsulfonamido]-1-benzenesulfonamide | CHEMBL161658 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H18ClN3O6S2 |
|---|
| Mol. Mass. | 519.978 |
|---|
| SMILES | NS(=O)(=O)c1cccc(NS(=O)(=O)c2ccc(NCc3cc(=O)oc4cc(Cl)ccc34)cc2)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
