| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Phenylethanolamine N-methyltransferase |
|---|
| Ligand | BDBM50080515 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_152560 |
|---|
| Ki | 640±n/a nM |
|---|
| Citation |  Grunewald, GL; McLeish, MJ; Criscione, KR Phenylethanolamine N-methyltransferase kinetics: bovine versus recombinant human enzyme. Bioorg Med Chem Lett11:1579-82 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Phenylethanolamine N-methyltransferase |
|---|
| Name: | Phenylethanolamine N-methyltransferase |
|---|
| Synonyms: | Noradrenaline N-methyltransferase | PNMT | PNMT_BOVIN | PNMTase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 30916.97 |
|---|
| Organism: | Bos taurus (bovine) |
|---|
| Description: | n/a |
|---|
| Residue: | 283 |
|---|
| Sequence: | MSGTDRSQAAGAVPDSDPGLAAVSSAYQRFEPRAYLRNNYAPPRGDLSCPDGVGPWKLRC
LAQTFATGEVSGRTLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELRLWLREEPGA
FDWSVYSQHVCLIEGKGESWQEKECQLRARVKRILPIDVHRPQPLGAGGLAPLPADALVS
AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLAVVPVREEEVR
EALVRTATRCGICARTPMPAHLQTGVDDVKGIFFTRAQKKVGV
|
|
|
|---|
| BDBM50080515 |
|---|
| n/a |
|---|
| Name | BDBM50080515 |
|---|
| Synonyms: | 7-Bromo-3-fluoromethyl-1,2,3,4-tetrahydro-isoquinoline | CHEMBL39928 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H11BrFN |
|---|
| Mol. Mass. | 244.103 |
|---|
| SMILES | FCC1Cc2ccc(Br)cc2CN1 |
|---|
| Structure | 
|
|---|
Search and Browse
