| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Phenylethanolamine N-methyltransferase |
|---|
| Ligand | BDBM13024 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_152574 |
|---|
| Ki | 950±n/a nM |
|---|
| Citation |  Grunewald, GL; McLeish, MJ; Criscione, KR Phenylethanolamine N-methyltransferase kinetics: bovine versus recombinant human enzyme. Bioorg Med Chem Lett11:1579-82 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Phenylethanolamine N-methyltransferase |
|---|
| Name: | Phenylethanolamine N-methyltransferase |
|---|
| Synonyms: | Noradrenaline N-methyltransferase | PENT | PNMT | PNMT_HUMAN | PNMTase | Phenylethanolamine N-Methyltransferase (PNMT) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 30852.66 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 282 |
|---|
| Sequence: | MSGADRSPNAGAAPDSAPGQAAVASAYQRFEPRAYLRNNYAPPRGDLCNPNGVGPWKLRC
LAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPGA
FNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALVS
AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEVR
EALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKVGL
|
|
|
|---|
| BDBM13024 |
|---|
| n/a |
|---|
| Name | BDBM13024 |
|---|
| Synonyms: | 7-sulfonamide-THIQ 14 | CHEMBL290890 | N-(4-chlorophenyl)-3-(fluoromethyl)-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H16ClFN2O2S |
|---|
| Mol. Mass. | 354.827 |
|---|
| SMILES | FCC1Cc2ccc(cc2CN1)S(=O)(=O)Nc1ccc(Cl)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
