Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM50101280 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_147175 |
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Ki | 543±n/a nM |
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Citation | Nortey, SO; Baxter, EW; Codd, EE; Zhang, SP; Reitz, AB Piperazinyl benzamidines: synthesis and affinity for the delta opioid receptor. Bioorg Med Chem Lett11:1741-3 (2001) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40465.04 |
Organism: | Rattus norvegicus (rat) |
Description: | Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor. |
Residue: | 372 |
Sequence: | MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTAC
TPSDGPGGGAAA
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BDBM50101280 |
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n/a |
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Name | BDBM50101280 |
Synonyms: | CHEMBL49741 | N,N-Diethyl-4-{(4-phenethyl-[1,4]diazepan-1-yl)-[(Z)-phenylimino]-methyl}-benzamide |
Type | Small organic molecule |
Emp. Form. | C31H38N4O |
Mol. Mass. | 482.6596 |
SMILES | CCN(CC)C(=O)c1ccc(cc1)C(=N\c1ccccc1)\N1CCCN(CCc2ccccc2)CC1 |
Structure |
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