Reaction Details |
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Target | Mu-type opioid receptor |
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Ligand | BDBM50101304 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_149137 |
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Ki | 1200±n/a nM |
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Citation | Nortey, SO; Baxter, EW; Codd, EE; Zhang, SP; Reitz, AB Piperazinyl benzamidines: synthesis and affinity for the delta opioid receptor. Bioorg Med Chem Lett11:1741-3 (2001) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Mu-type opioid receptor |
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Name: | Mu-type opioid receptor |
Synonyms: | MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 44503.11 |
Organism: | Rattus norvegicus (rat) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor. |
Residue: | 398 |
Sequence: | MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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BDBM50101304 |
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n/a |
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Name | BDBM50101304 |
Synonyms: | 4-{(4-Benzyl-piperazin-1-yl)-[(Z)-2-trifluoromethyl-phenylimino]-methyl}-N,N-diethyl-benzamide | CHEMBL301516 |
Type | Small organic molecule |
Emp. Form. | C30H33F3N4O |
Mol. Mass. | 522.6044 |
SMILES | CCN(CC)C(=O)c1ccc(cc1)C(=N\c1ccccc1C(F)(F)F)\N1CCN(Cc2ccccc2)CC1 |
Structure |
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